Horsechestnut is a European standardized extract containing 60 mg of the naturally occurring active compound aescin. Like all European herbal extracts, the extraction of our horsechestnut extract is regulated to the same high standards as over-the-counter drugs.
Horsechestnut seed extract is widely used in Europe to support healthy vein structure and function, both essential for normal, healthy circulation. Horsechestnut’s active agents include aescin and proanthocyanidin A2, with most of the biological effects being mediated by aescin. Aescin has been shown to support the normal, healthy structure and function of venous capillaries. This in turn provides support for normal venous circulation and healthy blood flow to the heart and other organs. Aescin appears to produce effects through a wide range of mechanisms including the synthesis of endothelial nitric oxide synthesis by making endothelial cells more permeable to calcium ions.
For chronic venous insufficiency, Horsechestnut may be a useful dietary supplement for those who wish to support a healthy structure and function of venous capillaries.
No adverse effects have been reported.
FORMULA (WW #10084)
1 Capsule Contains:
- Horsechestnut seed extract……………………………..300 mg
(Aesculus hippocastanum standardized to 20% [60 mg] Aescin)
Other Ingredients: gelatin, water (capsule), rice powder, cellulose, magnesium stearate, and silica.
This product contains NO sugar, salt, dairy, yeast, wheat, gluten, corn, soy, preservatives, artificial colors or flavors.
Adults take 1 capsule 3 times daily with meals or as directed by a healthcare professional.
Store in a cool, dry place, away from direct light. Keep out of reach of children.
- Sirtori CR. Aescin: pharmacology, pharmacokinetics and therapeutic profile. Pharmacol Res. 2001 Sep;44(3):183-93.
- Pittler MH, Ernst E (2006). Pittler, Max H. ed. “Horse chestnut seed extract for chronic venous insufficiency”. Cochrane Database Syst Rev (1): CD003230.
- Diehm C, Trampisch HJ, Lange S, Schmidt C (February 1996). “Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency”. Lancet 347 (8997): 292–294.
- Berti F, Omini C, Longiave D (August 1977). “The mode of action of aescin and the release of prostaglandins”. Prostaglandins 14 (2): 241–249.
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.